The Influence of Sulfanilamide upon the Yellow Pigment Formed by Mycobacterium tuberculosis from p-Aminobenzoic Acid.
نویسنده
چکیده
Previous reports from this laboratory have demonstrated that when a certain strain of Mycobacterium tuberculosis is cultured in Long's medium containing p-aminobenzoic acid (PABA), a yellow pigment is produced (Mayer, 1943, in press). Chemical analysis suggests that the pigment is, or contains, an unstable oxidation product of PABA, possibly a hydroxylamine derivative. The addition of Fe, Mg, glucose, ascorbic acid or NaCN to the medium exerts a definite influence on the activity of the PABA oxidase apparently involved in the formation of this pigment. The age of the culture and the hydrogen ion concentration are factors which also play roles. The present paper describes the results of a study concerned with the effect of sulfanilamide upon this same reaction.
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عنوان ژورنال:
- Journal of bacteriology
دوره 48 1 شماره
صفحات -
تاریخ انتشار 1944